Mouse clavicular development: Analysis of wild-type and cleidocranial dysplasia mutant mice
نویسندگان
چکیده
منابع مشابه
Cleidocranial dysplasia
Cleidocranial dysplasia (CCD) is an autosomal dominant disorder resulting in the skeletal and dental abnormalities due to the disturbance in ossification of the bones. Clavicle is the most commonly affected bone. The prevalence of CCD is one in millions of live births. In this report, we present a case of 10-years-old boy showing features of this condition.
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Cleidocranial dysplasia or mutational dysostosis or cleidocranial dysostosis is a generalized skeletodental dysplastic disorder, inherited in an autosomal dominant pattern. The expression of this disorder can vary widely in severity, even within the same family. This is a relatively rare disease and has no standard effective treatment option as of yet. Here we present a case report of affected ...
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متن کاملCleidocranial Dysplasia-Unearthing the Treasure
Cleidocranial dysplasia is an autosomal dominant condition caused by mutation of RUNX2, involving the skeleton and the teeth. It presents with a major finding of the hypoplasia or aplasia of clavicles along with late closure of the fontanels, presence of open skull sutures and multiple wormian bones. Although not frequent it can present to the dentist commonly with significant retention of mult...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 1997
ISSN: 1058-8388,1097-0177
DOI: 10.1002/(sici)1097-0177(199709)210:1<33::aid-aja4>3.0.co;2-2